Description

Alanine, n-[1-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Prolyl]-2-Methyl- (9Ci) is a specialized, high-purity protected amino acid derivative used in advanced organic synthesis. This compound is a critical building block for the solid-phase synthesis of complex peptides and peptidomimetics, offering precise control over molecular architecture. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected intermediate for the controlled assembly of custom peptide sequences.
• Pharmaceutical Research & Development: Serves as a crucial building block in the discovery and synthesis of peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Bioconjugation & Probe Development: Used to introduce specific functional groups or labels into peptides for diagnostic, imaging, or targeting applications.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse compound libraries for high-throughput screening in drug discovery.
• Biochemical Research: Utilized in academic and industrial labs to study protein-protein interactions, enzyme mechanisms, and signal transduction pathways.
• Production of Specialty Peptides: Enables the commercial-scale synthesis of therapeutic peptides, hormones, and cosmetic peptides.

Basic Information

Item	Details
Product Name	Alanine, n-[1-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Prolyl]-2-Methyl- (9Ci)
CAS No.	109772-44-3
Molecular Formula	C25H28N2O5
Molecular Weight	436.50 g/mol
Synonyms	Fmoc-L-Prolyl-2-methylalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-prolyl-2-methylalanine; Fmoc-Pro-2-MeAla-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(pyrrolidine-2-carbonyl)amino)-2-methylpropanoic acid; Nα-Fmoc-Nα-methyl-L-alanine proline derivative; Fmoc-2-methyl-Ala-Pro-OH; Protected amino acid derivative 109772-44-3
EINECS	Contact for details

Quality Control

Our Alanine, n-[1-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Prolyl]-2-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and peptide synthesis. Certificates of Analysis (COA) detailing purity, chiral integrity, and impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.