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L-Threoninamide, n-Acetyl-3-(2-Naphthalenyl)-D-Alanyl-L-Cysteinyl-L-Tyrosyl-D-Tryptophyl-L-Lysyl-L-Valyl-L-Cysteinyl-, Cyclic (2→7)-Disulfide CAS NO 109605-17-6
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CAS No.:109605-17-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
L-Threoninamide, n-Acetyl-3-(2-Naphthalenyl)-D-Alanyl-L-Cysteinyl-L-Tyrosyl-D-Tryptophyl-L-Lysyl-L-Valyl-L-Cysteinyl-, Cyclic (2→7)-Disulfide is a complex, synthetic peptide featuring a cyclic disulfide bridge, which is critical for stabilizing its bioactive conformation. This compound is of significant value in advanced pharmaceutical research and development, particularly for studying receptor-ligand interactions and as a potential scaffold for novel therapeutics. It is primarily needed by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in peptide-based drug discovery, endocrinology research, and the development of diagnostic agents.
Application
- Pharmaceutical R&D: Serves as a key intermediate or reference standard in the development of peptide-based drugs targeting G-protein-coupled receptors (GPCRs).
- Biochemical Research: Used as a high-affinity ligand or antagonist in receptor binding assays and signal transduction studies.
- Endocrinology Studies: Applied in research focused on hormone analogs and metabolic pathways due to its structural complexity.
- Diagnostic Development: Potential use in the creation of labeled probes or kits for clinical diagnostics and imaging.
- Peptide Chemistry: Acts as a model compound for studying disulfide bond formation, cyclization techniques, and peptide stability.
- Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for fundamental and applied life science research.
Basic Information
| Product Name | L-Threoninamide, n-Acetyl-3-(2-Naphthalenyl)-D-Alanyl-L-Cysteinyl-L-Tyrosyl-D-Tryptophyl-L-Lysyl-L-Valyl-L-Cysteinyl-, Cyclic (2→7)-Disulfide |
| CAS No. | 109605-17-6 |
| Molecular Formula | C58H74N12O13S2 |
| Molecular Weight | 1211.4 g/mol |
| Synonyms | Cyclo(2→7)-[Cys2,Cys7]-Ac-3-(2-Nal)-D-Ala-Cys-Tyr-D-Trp-Lys-Val-Cys-NH2; [Cys(Acm)2,7]-Somatostatin-14 Derivative; Ac-3-(2-Nal)-D-Ala-Cys-Tyr-D-Trp-Lys-Val-Cys-NH2 (cyclic 2-7 disulfide); Somatostatin Analog (cyclic); SRIF Analog; Peptide SRA-880 analog; CAS 109605-17-6 |
| EINECS | Contact for details |
Quality Control
Our L-Threoninamide, n-Acetyl-3-(2-Naphthalenyl)-D-Alanyl-L-Cysteinyl-L-Tyrosyl-D-Tryptophyl-L-Lysyl-L-Valyl-L-Cysteinyl-, Cyclic (2→7)-Disulfide is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development. Certificates of Analysis (COA) detailing purity, HPLC profile, and other critical parameters are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under inert atmosphere to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (MS) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Single Impurity (HPLC) | ≤ 2.0% |
| Water Content (KF) | ≤ 5.0% |
| Peptide Content | ≥ 80.0% |
| Disulfide Bond Integrity | Confirmed |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Rigorous Quality Assurance
Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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