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L-Threoninamide, n-Acetyl-3-(2-Naphthalenyl)-D-Alanyl-L-Cysteinyl-L-Tyrosyl-D-Tryptophyl-L-Lysyl-L-Valyl-L-Cysteinyl-, Cyclic (2→7)-Disulfide CAS NO 109605-17-6


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CAS No.:109605-17-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

L-Threoninamide, n-Acetyl-3-(2-Naphthalenyl)-D-Alanyl-L-Cysteinyl-L-Tyrosyl-D-Tryptophyl-L-Lysyl-L-Valyl-L-Cysteinyl-, Cyclic (2→7)-Disulfide is a complex, synthetic peptide featuring a cyclic disulfide bridge, which is critical for stabilizing its bioactive conformation. This compound is of significant value in advanced pharmaceutical research and development, particularly for studying receptor-ligand interactions and as a potential scaffold for novel therapeutics. It is primarily needed by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in peptide-based drug discovery, endocrinology research, and the development of diagnostic agents.

Application

  • Pharmaceutical R&D: Serves as a key intermediate or reference standard in the development of peptide-based drugs targeting G-protein-coupled receptors (GPCRs).
  • Biochemical Research: Used as a high-affinity ligand or antagonist in receptor binding assays and signal transduction studies.
  • Endocrinology Studies: Applied in research focused on hormone analogs and metabolic pathways due to its structural complexity.
  • Diagnostic Development: Potential use in the creation of labeled probes or kits for clinical diagnostics and imaging.
  • Peptide Chemistry: Acts as a model compound for studying disulfide bond formation, cyclization techniques, and peptide stability.
  • Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for fundamental and applied life science research.

Basic Information

Product Name L-Threoninamide, n-Acetyl-3-(2-Naphthalenyl)-D-Alanyl-L-Cysteinyl-L-Tyrosyl-D-Tryptophyl-L-Lysyl-L-Valyl-L-Cysteinyl-, Cyclic (2→7)-Disulfide
CAS No. 109605-17-6
Molecular Formula C58H74N12O13S2
Molecular Weight 1211.4 g/mol
Synonyms Cyclo(2→7)-[Cys2,Cys7]-Ac-3-(2-Nal)-D-Ala-Cys-Tyr-D-Trp-Lys-Val-Cys-NH2; [Cys(Acm)2,7]-Somatostatin-14 Derivative; Ac-3-(2-Nal)-D-Ala-Cys-Tyr-D-Trp-Lys-Val-Cys-NH2 (cyclic 2-7 disulfide); Somatostatin Analog (cyclic); SRIF Analog; Peptide SRA-880 analog; CAS 109605-17-6
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Quality Control

Our L-Threoninamide, n-Acetyl-3-(2-Naphthalenyl)-D-Alanyl-L-Cysteinyl-L-Tyrosyl-D-Tryptophyl-L-Lysyl-L-Valyl-L-Cysteinyl-, Cyclic (2→7)-Disulfide is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development. Certificates of Analysis (COA) detailing purity, HPLC profile, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under inert atmosphere to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 95.0%
Single Impurity (HPLC) ≤ 2.0%
Water Content (KF) ≤ 5.0%
Peptide Content ≥ 80.0%
Disulfide Bond Integrity Confirmed

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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