Description

2-Mercapto-6-Oxo-4-(2-Thienyl)-1,6-Dihydropyrimidine-5-Carbonitrile is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines pyrimidine, thiophene, and nitrile functionalities, making it a versatile precursor for creating complex pharmacophores. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for novel drug candidates, particularly in therapeutic areas targeting central nervous system disorders and metabolic diseases.
• Agrochemical Research: Used in the discovery and synthesis of new-generation pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science: Acts as a building block for organic electronic materials and ligands in catalytic systems due to its electron-rich thiophene and nitrile groups.
• Chemical Biology: Employed as a probe or scaffold in the development of enzyme inhibitors and molecular tools for biological research.
• Academic & Contract Research: Utilized in universities and CROs (Contract Research Organizations) for methodological studies and the exploration of new heterocyclic chemistry.

Basic Information

Product Name	2-Mercapto-6-Oxo-4-(2-Thienyl)-1,6-Dihydropyrimidine-5-Carbonitrile
CAS No.	109532-65-2
Molecular Formula	C9H5N3OS2
Molecular Weight	235.29 g/mol
Synonyms	4-(Thiophen-2-yl)-6-oxo-2-thioxo-1,2,3,6-tetrahydropyrimidine-5-carbonitrile; 4-(2-Thienyl)-2-mercapto-6-oxo-1,6-dihydropyrimidine-5-carbonitrile; 2-Thioxo-4-(2-thienyl)-6-oxo-1,6-dihydro-5-pyrimidinecarbonitrile; 5-Cyano-4-(2-thienyl)-2-mercapto-6-oxo-1,6-dihydropyrimidine; 4-(2-Thienyl)-2-thioxo-1,2,3,6-tetrahydropyrimidine-5-carbonitrile-6-one
EINECS	Contact for details

Quality Control

Our 2-Mercapto-6-Oxo-4-(2-Thienyl)-1,6-Dihydropyrimidine-5-Carbonitrile is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, prolonged exposure to light and air should be avoided. For long-term storage, consider an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.