Description

2-Nitro-4-(Trifluoromethyl)Benzaldehyde is a specialized aromatic aldehyde building block characterized by its nitro and trifluoromethyl substituents. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors where the introduction of fluorine atoms is crucial for modulating biological activity and stability. It is needed by research chemists and process development teams in fine chemical, pharmaceutical, and advanced material industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and dyes due to its electron-withdrawing groups.
• Custom Synthesis & Contract Manufacturing: A valuable building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2-Nitro-4-(Trifluoromethyl)Benzaldehyde
CAS No.	109466-87-7
Molecular Formula	C8H4F3NO3
Molecular Weight	219.12 g/mol
Synonyms	4-(Trifluoromethyl)-2-nitrobenzaldehyde; 2-Nitro-α,α,α-trifluoro-p-tolualdehyde; 2-Nitro-4-trifluoromethylbenzaldehyde; Benzaldehyde, 2-nitro-4-(trifluoromethyl)-; p-(Trifluoromethyl)-o-nitrobenzaldehyde
EINECS	Contact for details

Quality Control

Our 2-Nitro-4-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.