Description

5-(Thiophen-2-Yl)Pyrimidine-2,4(1H,3H)-Dione is a high-value heterocyclic organic compound featuring a fused pyrimidine-dione core substituted with a thiophene ring. This unique molecular architecture makes it a critical pharmaceutical intermediate and a versatile building block for advanced material science. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, antiviral agents, and enzyme inhibitors.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Acts as a monomer or functional unit in the creation of organic semiconductors, conductive polymers, and advanced organic frameworks (MOFs/COFs).
• Chemical Synthesis: Employed as a versatile scaffold in organic chemistry for constructing complex heterocyclic compounds through further functionalization.
• Biochemical Research: Utilized in life science research as a probe or inhibitor to study biological pathways and enzyme functions.
• Dye & Pigment Industry: Functions as an intermediate for synthesizing specialized dyes and pigments with specific light-absorption properties.

Basic Information

Item	Detail
Product Name	5-(Thiophen-2-Yl)Pyrimidine-2,4(1H,3H)-Dione
CAS No.	109299-90-3
Molecular Formula	C8H6N2O2S
Molecular Weight	194.21 g/mol
Synonyms	5-(2-Thienyl)-2,4(1H,3H)-pyrimidinedione; 5-(Thiophen-2-yl)pyrimidine-2,4-diol; 5-(2-Thienyl)uracil; 5-(2-Thienyl)-2,4-dihydroxypyrimidine; 5-(Thiophen-2-yl)-1H-pyrimidine-2,4-dione; 5-(2-Thienyl)-1H-pyrimidine-2,4-dione; 5-(2-Thienyl)pyrimidine-2,4(1H,3H)-dione
EINECS	Contact for details

Quality Control

Our production of 5-(Thiophen-2-Yl)Pyrimidine-2,4(1H,3H)-Dione adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis, to ensure it meets precise customer specifications. A Certificate of Analysis (COA) documenting all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.