Description

5-Pyrimidinylboronic Acid is a versatile and high-value boronic acid derivative, essential as a key building block in modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex pyrimidine-containing molecules through cross-coupling reactions. This compound is critically needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that contain the pyrimidine pharmacophore.
• Material Science & OLED Development: Serves as a building block for creating organic electronic materials, including ligands for metal-organic frameworks (MOFs) and emissive layers in OLED devices.
• Chemical Biology & Probe Synthesis: Employed in the synthesis of molecular probes and bioconjugates for studying biological processes and diagnostic applications.
• Academic & Process Chemistry: A standard reagent in research laboratories for methodological development and scaling up synthetic routes to complex molecules.

Basic Information

Product Name	5-Pyrimidinylboronic Acid
CAS No.	109299-78-7
Molecular Formula	C4H5BN2O2
Molecular Weight	123.91 g/mol
Synonyms	5-Pyrimidineboronic Acid; (Pyrimidin-5-yl)boronic Acid; 5-Boronopyrimidine; Pyrimidin-5-ylboronic Acid; 5-Pyrimidylboronic Acid; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine (Pinacol Ester); 109299-78-7 (CAS)
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinylboronic Acid is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.