Description

Vasotocin, 1-Desamino-(4-Azidobenzoyl)Lys(7)-Arg(8)- is a chemically modified, non-mammalian neurohypophysial hormone analog designed for advanced biochemical research and development. This specialized peptide is engineered with a photoreactive azidobenzoyl group, making it a critical tool for studying vasotocin receptor interactions, binding sites, and signal transduction pathways through photoaffinity labeling techniques. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies focused on neuroendocrinology, comparative physiology, and novel drug discovery.

Application

• Photoaffinity Labeling Studies: A key reagent for covalently tagging and identifying vasotocin (VT) and related neurohypophysial hormone receptors in tissue samples or purified protein preparations.
• Receptor Mapping & Characterization: Used to elucidate the structure-activity relationships (SAR) and binding domains of vasotocin receptors in non-mammalian vertebrates (e.g., birds, fish, amphibians).
• Biochemical Probe Development: Serves as a foundational compound for creating advanced probes to study the physiological roles of vasotocin in osmoregulation, social behavior, and reproduction.
• Comparative Endocrinology Research: Facilitates research into the evolution and functional divergence of the vasopressin/oxytocin hormone family across different species.
• Lead Compound in Drug Discovery: Provides a modified peptide scaffold for the development of novel agonists or antagonists targeting vasotocin pathways for potential therapeutic applications.
• Cross-linking Agent for Mass Spectrometry: Enables the isolation and analysis of receptor-ligand complexes in proteomic studies to understand protein-protein interactions.

Basic Information

Product Name	Vasotocin, 1-Desamino-(4-Azidobenzoyl)Lys(7)-Arg(8)-
CAS No.	109064-94-0
Molecular Formula	C52H78N18O12S2
Molecular Weight	1187.42 g/mol
Synonyms	1-Desamino-4-azidobenzoyl-[Lys7, Arg8]-vasotocin; [4-Azidobenzoyl-Lys7, Arg8]-Vasotocin; p-Azidobenzoyl-Lys7-Arg8-Vasotocin; Photoaffinity Vasotocin Analog; VT Photoaffinity Label; AVT analog; Cys-Tyr-Ile-Gln-Asn-Cys-Pro-(4-Azidobenzoyl)Lys-Arg-NH2 (cyclic 1-6 disulfide)
EINECS	Contact for details

Quality Control

Our Vasotocin, 1-Desamino-(4-Azidobenzoyl)Lys(7)-Arg(8)- is produced under stringent conditions suitable for research applications. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing results for HPLC purity, amino acid analysis, mass spectrometry (MS), and correct disulfide bond formation are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Amino Acid Analysis	Within ± 10% of theoretical composition
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80% (by weight)
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.