Description

Vasotocin, 1-Deamino-7-Lys-8-Arg- is a synthetic analogue of the neurohypophysial hormone vasotocin, characterized by specific amino acid substitutions that enhance its stability and receptor binding profile. This compound is of significant interest for advanced research in neuroendocrinology and comparative physiology. It serves as a critical tool for scientists investigating the role of vasotocin and related peptides in behavioral regulation, osmoregulation, and social functions across various species. The product is supplied to meet the stringent requirements of pharmaceutical R&D and academic research institutions globally.

Application

• Neuroendocrine Research: Used as a reference standard and active agent in studies exploring the physiological and behavioral effects of vasotocin-like peptides.
• Comparative Physiology Studies: Essential for investigating the evolutionary biology of the vasopressin/oxytocin hormone family in non-mammalian vertebrates.
• Receptor Binding Assays: Employed in competitive binding studies to characterize and map vasotocin receptor subtypes (V1a, V1b, V2-type) in different tissues.
• Biochemical Pathway Analysis: A key reagent for elucidating intracellular signaling cascades activated by vasotocin receptor engagement.
• Pharmaceutical Development: Serves as a lead compound or intermediate in the discovery of novel therapeutics targeting vasopressin-related disorders.
• Veterinary Science Research: Applied in studies related to avian, reptilian, and amphibian physiology, particularly concerning water balance and stress responses.

Basic Information

Product Name	Vasotocin, 1-Deamino-7-Lys-8-Arg-
CAS No.	109064-92-8
Molecular Formula	C46H74N16O12S2
Molecular Weight	1083.3 g/mol
Synonyms	1-Deamino-8-arginine-7-lysine-vasotocin; [Lys8]-Vasotocin; dAVT; Desamino-[Arg8, Lys7]-Vasotocin; 1-β-Mercaptopropionic acid-8-arginine-7-lysine-vasotocin; (1-Deamino-7-Lysine-8-Arginine)-Vasotocin; Vasotocin analogue (1-deamino,7-Lys,8-Arg); [7-Lysine, 8-Arginine]-Vasotocin (1-deamino-)
EINECS	Contact for details

Quality Control

Our Vasotocin, 1-Deamino-7-Lys-8-Arg- is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, critical for research reproducibility. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all test results are provided and available upon request. We adhere to a quality management system to support the needs of GLP (Good Laboratory Practice) and research-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%
Solubility	Soluble in water, acetic acid (dilute)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.