Description

Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln is a synthetic heptapeptide with the sequence Glycine-Proline-Leucine-Glycine-Isoleucine-Alanine-Glycine-Glutamine. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a specific substrate or model sequence for studying enzyme kinetics, particularly for proteases like collagenase. It serves as a critical tool for researchers and manufacturers in the fields of proteomics, enzymology, and peptide-based drug discovery. The product is supplied as a high-purity material suitable for laboratory and development-scale applications.

Application

• Enzymology Research: Used as a specific, cleavable substrate for studying the activity and inhibition of matrix metalloproteinases (MMPs) and other proteolytic enzymes.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the development of peptide-based therapeutics and diagnostic agents.
• Biochemical Assays: Employed in high-throughput screening (HTS) assays to identify and characterize novel enzyme inhibitors for therapeutic targets.
• Academic Research: Utilized in university and institutional labs for fundamental studies on protein-peptide interactions and degradation pathways.
• Quality Control: Acts as a reference standard for the quality assurance and purity testing of related peptide products and complex biological samples.

Basic Information

Product Name	Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln
CAS No.	109053-09-0
Molecular Formula	C31H52N8O10
Molecular Weight	696.80 g/mol
Synonyms	GPLGIAGQ; Heptapeptide GPLGIAGQ; Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln peptide; MMP Substrate GPLGIAGQ; Collagenase Substrate; GP-Leu-Gly-Ile-Ala-Gly-Gln; H-Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln-OH
EINECS	Contact for details

Quality Control

Our Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.