Description

Glutarylcarnitine is a specialized acylcarnitine derivative, a key intermediate in mitochondrial fatty acid and amino acid metabolism. This high-purity compound is essential for research and development in metabolic studies and diagnostic applications. It is primarily utilized by biotech and pharmaceutical companies, clinical research organizations, and diagnostic kit manufacturers focused on inborn errors of metabolism, such as glutaric acidemia.

Application

• Biomarker Research & Diagnostic Assays: Used as a critical reference standard in LC-MS/MS methods for the quantitative analysis of acylcarnitine profiles in plasma and dried blood spots.
• Inborn Errors of Metabolism (IEM) Studies: Essential for investigating metabolic pathways in disorders like glutaric acidemia type I (GA-I), serving as a substrate or analyte in enzymatic activity tests and metabolic flux studies.
• Pharmaceutical R&D: Employed in drug discovery programs targeting metabolic diseases, for cell-based assays, and in the development of potential therapeutic monitoring protocols.
• Clinical Chemistry: Incorporated into quality control materials and calibrators for newborn screening and specialized clinical chemistry tests to ensure accurate diagnosis.
• Nutritional & Biochemical Research: Used in studies exploring carnitine shuttle function, energy metabolism, and the biochemical effects of nutritional interventions.

Basic Information

Product Name	Glutarylcarnitine
CAS No.	109006-11-3
Molecular Formula	C12H21NO7
Molecular Weight	291.30 g/mol
Synonyms	Glutarylcarnitine; L-Glutarylcarnitine; O-Glutarylcarnitine; (3R)-3-[(3-Carboxypropanoyl)oxy]-4-(trimethylammonio)butanoate; Glutarylcarnitine inner salt; Glutarylcarnitine zwitterion; C5-DC; Glutaroylcarnitine
EINECS	Contact for details

Quality Control

Every batch of Glutarylcarnitine is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to support its use as a high-grade reference material. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0% w/w
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.