Description

(Glu3)-Glucagon (1-29) (Human, Rat, Porcine) is a synthetic peptide analog of the glucagon hormone, specifically modified at the third position with a glutamic acid residue. This engineered peptide is critical for advanced biochemical research and pharmaceutical development, offering a valuable tool for studying metabolic pathways and receptor interactions. It is primarily utilized by research institutions, diagnostic manufacturers, and biopharmaceutical companies engaged in diabetes, obesity, and metabolic disorder research, as well as in the development of novel therapeutic agents and diagnostic assays.

Application

• Biomedical Research: A key reagent for studying glucagon receptor (GCGR) signaling, hormone action, and glucose metabolism in vitro and in vivo.
• Pharmaceutical Development: Used as a reference standard or active pharmaceutical ingredient (API) intermediate in the development of metabolic disorder therapeutics.
• Diagnostic Assays: Serves as a critical component in the calibration and validation of immunoassays (e.g., ELISA, RIA) for glucagon measurement.
• Metabolic Studies: Employed in preclinical research to investigate the physiological effects of glucagon analogs on liver function and energy homeostasis.
• Academic Research: Utilized in university and institutional labs for fundamental endocrinology and peptide hormone research.
• Quality Control: Acts as a system suitability standard in analytical laboratories for peptide purity and identity testing.

Basic Information

Product Name	(Glu3)-Glucagon (1-29) (Human, Rat, Porcine)
CAS No.	108997-34-8
Molecular Formula	C153H225N43O49S
Molecular Weight	3483.8 g/mol
Synonyms	Glucagon (1-29), human, porcine, rat, Glu3-glucagon; [Glu3]-Glucagon; Glucagon, 3-L-glutamic acid-; H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH; Glucagon Fragment 1-29; Synthetic Glucagon Analog
EINECS	Contact for details

Quality Control

Our (Glu3)-Glucagon (1-29) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. We provide comprehensive Certificates of Analysis (COA) detailing all specifications to ensure traceability and compliance with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate and keep frozen. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.