Description

Suc-Ala-Ala-Pro-Lys-Pna CAS NO 108929-39-1 is a chromogenic peptide substrate designed for the specific detection and quantification of serine protease activity. This compound is critical for biochemical research and diagnostic applications, providing a reliable and sensitive means to measure enzyme kinetics and inhibition. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and life science sectors for enzyme assay development and high-throughput screening.

Application

• Enzyme Activity Assays: Primary substrate for the spectrophotometric or fluorometric determination of serine protease activity, including trypsin, plasmin, and related enzymes.
• Drug Discovery & High-Throughput Screening (HTS): Used in pharmaceutical R&D to screen for potential protease inhibitors as therapeutic candidates.
• Biochemical Research: Essential tool for studying enzyme kinetics, mechanism of action, and substrate specificity in academic and industrial laboratories.
• Diagnostic Kit Development: Incorporated into in-vitro diagnostic (IVD) kits for clinical testing of conditions related to protease imbalances.
• Quality Control in Biomanufacturing: Employed to monitor and validate the activity of protease enzymes used in bioprocessing and production.

Basic Information

Product Name	Suc-Ala-Ala-Pro-Lys-Pna
CAS No.	108929-39-1
Molecular Formula	C30H44N8O10
Molecular Weight	676.73 g/mol
Synonyms	Suc-AAPK-pNA; N-Succinyl-Ala-Ala-Pro-Lys p-nitroanilide; Succinyl-Alanyl-Alanyl-Prolyl-Lysine 4-Nitroanilide; Suc-AAPK-pNA Substrate; Chromogenic Substrate for Serine Proteases; AAPK-pNA; Trypsin Chromogenic Substrate; Protease Substrate 108929-39-1
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and performance. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request. We adhere to stringent quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in DMSO, DMF; slightly soluble in water
Functional Activity	Cleavage by target protease produces a measurable increase in absorbance at 405 nm.

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.