Description

Lhrh (2-10), Trp(6)- CAS NO 108787-46-8 is a synthetic peptide fragment of the Luteinizing Hormone-Releasing Hormone (LHRH), specifically the sequence from amino acids 2 to 10 with a tryptophan substitution at position 6. This compound is a critical intermediate and research tool for the development and study of hormone analogs and therapeutic agents. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on endocrinology, oncology, and reproductive medicine.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of novel LHRH agonist and antagonist analogs for therapeutic applications.
• Biochemical Studies: Used to investigate hormone-receptor interactions, signal transduction pathways, and structure-activity relationships (SAR) of peptide hormones.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in peptide manufacturing and analysis.
• Preclinical Development: Employed in the formulation and testing of potential drug candidates targeting hormone-dependent conditions.
• Academic Research: A vital reagent for studies in endocrinology, reproductive biology, and cancer research within university and institutional labs.
• Peptide Library Construction: Used as a building block or template for creating specialized peptide libraries for screening purposes.

Basic Information

Product Name	Lhrh (2-10), Trp(6)- CAS NO 108787-46-8
CAS No.	108787-46-8
Molecular Formula	C53H74N16O12
Molecular Weight	1119.3 g/mol
Synonyms	LHRH (2-10), Trp(6)-; [Trp6]-LHRH (2-10); Luteinizing Hormone-Releasing Hormone (2-10) fragment, Trp(6)-substituted; pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 (2-10 fragment with Trp6); Gonadorelin (2-10) fragment analog; LH-RH (2-10), [Trp6]-; [Trp6]-Gonadorelin (2-10); Luliberin (2-10) fragment, [Trp6]-
EINECS	Contact for details

Quality Control

Our Lhrh (2-10), Trp(6)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.