Description

1,2,4-Triazolo[4,3-A]Pyrimidin-3(2H)-One, 2-(Chloroacetyl)-5,6,7,8-Tetrahydro- (9Ci) is a high-value, heterocyclic organic compound featuring a fused triazolopyrimidine core with a reactive chloroacetyl side chain. This structure makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Serves as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Medicinal Chemistry Research: Used extensively in high-throughput screening and structure-activity relationship (SAR) studies to explore new therapeutic avenues.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme function and biological pathways due to its reactive functional group.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized heterocyclic chemistry.

Basic Information

Product Name	1,2,4-Triazolo[4,3-A]Pyrimidin-3(2H)-One, 2-(Chloroacetyl)-5,6,7,8-Tetrahydro- (9Ci)
CAS No.	108735-50-8
Molecular Formula	C8H9ClN4O2
Molecular Weight	228.64 g/mol
Synonyms	2-(Chloroacetyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrimidin-3(2H)-one; 2-Chloro-1-(5,6,7,8-tetrahydro-3-oxo-1,2,4-triazolo[4,3-a]pyrimidin-2-yl)ethanone; 108735-50-8; 2-(Chloroacetyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrimidin-3(2H)-one; Ethanone, 2-chloro-1-(5,6,7,8-tetrahydro-3-oxo[1,2,4]triazolo[4,3-a]pyrimidin-2-yl)-
EINECS	Contact for details

Quality Control

Every batch of our 1,2,4-Triazolo[4,3-A]Pyrimidin-3(2H)-One, 2-(Chloroacetyl)-5,6,7,8-Tetrahydro- (9Ci) is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the precise requirements of research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments, supporting regulatory submissions and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.