Description

Ac-Met(O)-Oh CAS NO 108646-71-5 is a chemically modified amino acid derivative, specifically the oxidized form of methionine. This high-purity compound is critical for advanced research and development in life sciences, where precise molecular structure is paramount. It serves as a key intermediate and building block for pharmaceutical synthesis, peptide chemistry, and biochemical studies, enabling innovation in drug discovery and proteomics.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate oxidized methionine residues into peptide chains for research and development.
• Biochemical Research: Employed as a standard or reagent in proteomics research, enzyme studies, and investigations into oxidative stress and protein modification.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in HPLC, LC-MS, and other analytical techniques.
• Proteomics & Biomarker Discovery: Utilized in the study of post-translational modifications and as a tool for mass spectrometry calibration and protein characterization.

Basic Information

Product Name	Ac-Met(O)-Oh
CAS No.	108646-71-5
Molecular Formula	C7H13NO4S
Molecular Weight	207.25 g/mol
Synonyms	N-Acetyl-L-methionine sulfoxide; Acetyl-L-methionine sulfoxide; Ac-Met(O)-OH; L-Methionine, N-acetyl-, sulfoxide; N-Acetylmethionine S-oxide; N-Acetyl-L-methionine S-oxide; Acetyl methionine sulfoxide; (2S)-2-Acetamido-4-(methylsulfinyl)butanoic acid
EINECS	Contact for details

Quality Control

Our Ac-Met(O)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP guidelines for pharmaceutical intermediates, and specifications can be tailored to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]²⁰D: Specific range available on COA
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.