Description

Magainin I is a naturally occurring antimicrobial peptide originally isolated from the skin of the African clawed frog, *Xenopus laevis*. This compound is of significant interest for its broad-spectrum activity against bacteria, fungi, and protozoa, making it a valuable model compound in the study of host defense peptides and novel antibiotic development. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for antimicrobial research, drug discovery, and the development of novel therapeutic agents.

Application

• Antimicrobial Research: Serves as a key reference standard and active agent in studies investigating the mechanisms of action of cationic antimicrobial peptides (AMPs).
• Drug Discovery & Development: Used as a lead compound or template for designing novel peptide-based antibiotics and anti-infective agents with improved stability and efficacy.
• Biomaterial & Coating Development: Incorporated into research for developing antimicrobial surfaces, coatings, and medical devices to prevent biofilm formation and infections.
• Biochemical & Biophysical Studies: Employed in structural analysis, membrane interaction studies, and understanding peptide-lipid bilayer dynamics.
• Cosmeceutical & Personal Care Research: Investigated for potential applications in formulations targeting skin microbiota and as a preservative alternative.
• Veterinary & Agricultural Research: Explored for developing novel treatments for animal infections and as a potential agent in crop protection strategies.

Basic Information

Product Name	Magainin I
CAS No.	108433-99-4
Molecular Formula	C₁₀₆H₁₆₉N₃₁O₃₁
Molecular Weight	~2466.8 g/mol
Synonyms	Magainin 1; PGS; Peptide Glycine-Leucine Amide; Xenopsin precursor fragment; Antimicrobial peptide magainin I; Magainin-1; Magainin A; IIGKFLHSAKKFGKAFVGEIMNS
EINECS	Contact for details

Quality Control

Our Magainin I is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for research purposes. Each lot is characterized using advanced analytical techniques, including HPLC for purity assessment and mass spectrometry for identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and analytical data is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Conforms to theoretical composition
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC/IC)	Reported on COA
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.