Description

Magainin Ii CAS NO 108433-95-0 is a naturally occurring antimicrobial peptide originally isolated from the skin of the African clawed frog, *Xenopus laevis*. This compound is of significant interest for its broad-spectrum activity against bacteria, fungi, and protozoa, making it a valuable research tool for studying host defense mechanisms and developing novel therapeutic agents. It is primarily utilized by researchers and developers in the fields of pharmaceutical R&D, microbiology, and biotechnology for investigating new antibiotic pathways and peptide-based drug candidates.

Application

• Antimicrobial Research: Used as a model peptide to study mechanisms of membrane disruption and antimicrobial activity against Gram-positive and Gram-negative bacteria.
• Drug Discovery: Serves as a lead compound or template for the development of novel synthetic antimicrobial peptides (AMPs) with enhanced stability and efficacy.
• Biomaterial Coatings: Investigated for incorporation into medical device coatings, wound dressings, and implant surfaces to prevent biofilm formation and infection.
• Cosmeceutical Research: Explored for potential applications in skincare formulations for its antimicrobial and possible wound-healing properties.
• Veterinary Medicine: Studied for potential use as an alternative to conventional antibiotics in animal health applications.
• Academic & Institutional Research: A key reagent in university and institutional labs for fundamental research in immunology, peptide chemistry, and molecular biology.

Basic Information

Product Name	Magainin Ii
CAS No.	108433-95-0
Molecular Formula	C106H159N31O26S
Molecular Weight	~ 2267.7 g/mol
Synonyms	Magainin 2; Magainin II; PGS; Peptide Glycine-Leucine Amide; Xenopsin precursor fragment; Antimicrobial peptide magainin-2; IIGWLSKKGAFGGEVIMNS
EINECS	Contact for details

Quality Control

Our Magainin Ii is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for critical research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other relevant analytical data. We adhere to rigorous quality testing protocols to meet the exacting standards required for research-grade peptides.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.