Description

H-Leu-Leu-Phe-Nh2 CAS NO 108370-29-2 is a high-purity synthetic tripeptide derivative, specifically a protected peptide amide, valued for its role as a critical intermediate and building block in advanced organic synthesis. Its precise molecular structure makes it an essential component for research and development in peptide chemistry and pharmaceutical manufacturing. This compound is primarily utilized by R&D laboratories, fine chemical producers, and pharmaceutical companies engaged in the development of novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and proteomics research to investigate protease activity and protein-protein interactions.
• Peptide Library Synthesis: A valuable component in combinatorial chemistry for creating diverse peptide libraries used in high-throughput screening for drug discovery.
• Academic & Industrial R&D: Employed in universities and corporate R&D departments for method development and fundamental studies in peptide coupling and deprotection strategies.
• Fine Chemical Production: Acts as a specialized intermediate for custom synthesis services catering to the biotechnology and diagnostic industries.

Basic Information

Product Name	H-Leu-Leu-Phe-Nh2
CAS No.	108370-29-2
Molecular Formula	C24H38N4O4
Molecular Weight	446.58 g/mol
Synonyms	H-Leu-Leu-Phe-NH2; Leu-Leu-Phe amide; L-Leucyl-L-leucyl-L-phenylalaninamide; N-(L-Leucyl)-L-leucyl-L-phenylalaninamide; LLF-NH2; Tripeptide amide LLF; Boc-LLF-NH2 (protected form); Fmoc-LLF-NH2 (protected form)
EINECS	Contact for details

Quality Control

Our H-Leu-Leu-Phe-Nh2 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to verify enantiomeric purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.