Description

H-D-Tyr(Po3H2)-Oh is a phosphorylated tyrosine derivative, specifically the D-isomer of O-phospho-L-tyrosine, with the CAS number 108321-25-1. This modified amino acid is a critical building block and research tool in biochemistry and medicinal chemistry, enabling the study of phosphorylation-dependent signaling pathways. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who are developing peptide-based therapeutics, kinase inhibitors, or diagnostic assays.

Application

• Peptide Synthesis: As a key phosphorylated amino acid residue for the solid-phase or solution-phase synthesis of biologically active phosphopeptides.
• Biochemical Research: Used as a standard, substrate, or inhibitor in enzymatic studies related to protein kinases, phosphatases, and signal transduction mechanisms.
• Pharmaceutical Development: Serves as a crucial intermediate in the research and development of targeted cancer therapies and other drugs that modulate phosphorylation events.
• Diagnostic Reagent Production: Incorporated into the design of antigens for producing antibodies specific to phosphotyrosine, used in ELISA, Western blotting, and immunohistochemistry.
• Proteomics & Mass Spectrometry: Employed as a reference compound for the identification and quantification of phosphorylated peptides in complex biological samples.

Basic Information

Product Name	H-D-Tyr(Po3H2)-Oh
CAS No.	108321-25-1
Molecular Formula	C9H12NO6P
Molecular Weight	261.17 g/mol
Synonyms	D-O-Phosphotyrosine; (R)-2-Amino-3-(4-phosphonoxyphenyl)propanoic acid; H-D-Tyr(PO3H2)-OH; D-Phosphotyrosine; D-pTyr; D-Tyr(P); D-4-Phosphonoxyphenylalanine; Fmoc-D-Tyr(PO3H2)-OH (precursor form)
EINECS	Contact for details

Quality Control

Our H-D-Tyr(Po3H2)-Oh is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Optical Rotation	Specific rotation provided per COA
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.