Description

n-Cbz-Ala-Pro-Leu Dicyclohexylammonium Salt is a protected peptide derivative used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates for the development of novel peptide-based pharmaceuticals and biochemical tools. It is particularly valuable for applications in medicinal chemistry, proteomics research, and the synthesis of complex bioactive molecules where precise structural control is paramount.

Application

• Pharmaceutical Intermediate: Serves as a key protected fragment in the solid-phase and solution-phase synthesis of therapeutic peptides.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of enzyme inhibitors or receptor agonists/antagonists.
• Bioconjugation: Acts as a precursor for creating peptide-drug conjugates or labeled peptides for diagnostic applications.
• Biochemical Tool Development: Employed in the preparation of substrates for protease and peptidase enzyme assays.
• Academic & Industrial R&D: A fundamental reagent for exploring new synthetic methodologies and peptide mimetics in laboratory settings.

Basic Information

Product Name	n-Cbz-Ala-Pro-Leu Dicyclohexylammonium Salt
CAS No.	108321-20-6
Molecular Formula	C₃₃H₅₄N₄O₆
Molecular Weight	618.81 g/mol
Synonyms	Carbobenzoxy-Ala-Pro-Leu Dicyclohexylammonium Salt; Z-Ala-Pro-Leu DCHA Salt; Nα-Carbobenzyloxy-L-alanyl-L-prolyl-L-leucine Dicyclohexylammonium Salt; CBZ-Ala-Pro-Leu·DCHA; Benzyloxycarbonyl-Ala-Pro-Leu Dicyclohexylamine Salt; Ala-Pro-Leu Z-DCHA; L-Alanyl-L-prolyl-L-leucine, N-[(phenylmethoxy)carbonyl]-, compd. with N-cyclohexylcyclohexanamine (1:1)
EINECS	Contact for details

Quality Control

Our n-Cbz-Ala-Pro-Leu Dicyclohexylammonium Salt is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant guidelines for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.