Description

H-Phe-Leu-Nh2 Hbr is a high-purity dipeptide derivative, specifically the hydrobromide salt of the phenylalanine-leucine amide. This compound serves as a critical building block (intermediate) in advanced pharmaceutical research and peptide synthesis. It is primarily utilized by R&D laboratories and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or standard in enzymatic studies, metabolic pathway analysis, and proteomics research.
• Peptide Library Construction: An essential component in solid-phase and solution-phase peptide synthesis for creating diverse compound libraries for screening.
• Protease/Enzyme Studies: Employed to investigate enzyme kinetics, specificity, and inhibition mechanisms of proteolytic enzymes.
• Neuroscience Research: Potential use in studying neuropeptide analogs and their interactions with receptors.
• Cosmetic Peptide Synthesis: Can be utilized in the development of specialized bioactive peptides for advanced skincare formulations.

Basic Information

Product Name	H-Phe-Leu-Nh2 Hbr
CAS No.	108321-16-0
Molecular Formula	C15H23N3O2 • HBr
Molecular Weight	358.28 g/mol
Synonyms	L-Phenylalanyl-L-leucinamide hydrobromide; Phe-Leu-NH2 • HBr; F-L-NH2 HBr; H-Phe-Leu-NH2 • HBr; N-(L-Phenylalanyl)-L-leucinamide hydrobromide; (S)-2-((S)-2-Amino-3-phenylpropanamido)-4-methylpentanamide hydrobromide; Phenylalanine-leucine amide HBr salt; F-L-NH2•HBr
EINECS	Contact for details

Quality Control

Our H-Phe-Leu-Nh2 Hbr is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity verification, and identity confirmation to ensure it meets the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.