Description

H-Thr-Asp-Oh is a high-purity, protected dipeptide building block, essential for advanced peptide synthesis. Its primary value lies in providing a precisely defined molecular fragment, enabling researchers and manufacturers to construct complex peptides with high fidelity and efficiency. This compound is critically needed by pharmaceutical R&D teams, biotechnology companies, and fine chemical suppliers engaged in the development of therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled assembly of longer peptide chains in automated synthesizers.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based drugs targeting various diseases.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, polymers, or surfaces.
• Biochemical Reagent Production: A precursor for synthesizing specialized reagents, enzyme substrates, or inhibitors used in life science research.
• Custom Peptide Services: A fundamental building block supplied to CROs and CDMOs offering bespoke peptide manufacturing.
• Academic Research: Utilized in university and institutional labs for studying protein structure, function, and peptide chemistry.

Basic Information

Product Name	H-Thr-Asp-Oh
CAS No.	108320-97-4
Molecular Formula	C8H14N2O6
Molecular Weight	234.21 g/mol
Synonyms	L-Threonyl-L-aspartic acid; H-Thr-Asp-OH; Thr-Asp; L-Thr-L-Asp; Aspartylthreonine; N-(2-((S)-2-Amino-3-hydroxybutanamido)-1-carboxyethyl)-L-aspartic acid; Fmoc-Thr(tBu)-Asp(OtBu)-OH (protected precursor); Boc-Thr(Bzl)-Asp(OBzl)-OH (protected precursor)
EINECS	Contact for details

Quality Control

Our H-Thr-Asp-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via MS and NMR. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.