Description

N1-Glutathionyl-Spermidine Disulfide is a specialized, high-purity biochemical compound of significant interest in advanced research and development. This molecule, formed from the conjugation of glutathione and spermidine, serves as a critical tool for studying cellular redox regulation, polyamine metabolism, and oxidative stress pathways. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for applications ranging from novel therapeutic discovery to fundamental biochemical mechanism studies.

Application

• Biochemical Research: A key reagent for investigating the role of glutathionylated polyamines in cellular signaling, apoptosis, and antioxidant defense mechanisms.
• Pharmaceutical Development: Used as a reference standard or intermediate in the R&D of therapeutics targeting oxidative stress-related diseases, neurodegenerative disorders, and cancer.
• Enzymology Studies: Serves as a substrate or inhibitor for studying enzymes involved in glutathione and polyamine metabolism, such as transglutaminases and oxidoreductases.
• Nutritional Science Research: Investigated for its potential role in cellular health, aging, and as a biomarker for oxidative status in nutritional studies.
• Diagnostic Assay Development: Potential use in developing assays to detect and quantify glutathionylated metabolites in biological samples for clinical research.

Basic Information

Product Name	N1-Glutathionyl-Spermidine Disulfide
CAS No.	108081-77-2
Molecular Formula	C22H42N8O7S2
Molecular Weight	594.75 g/mol
Synonyms	Glutathionylspermidine Disulfide; N1-(Glutathionyl)spermidine Disulfide; Gspd Disulfide; γ-Glutamylcysteinylglycyl-spermidine Disulfide; L-γ-Glutamyl-L-cysteinylglycyl-N1-spermidine Disulfide; Trypanothione Disulfide (isomeric form); Bis(glutathionyl)spermidine Disulfide (related); GSSpd
EINECS	Contact for details

Quality Control

Our N1-Glutathionyl-Spermidine Disulfide is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific research-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This compound is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and exposure to air.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.