Description

Cholecystokinin 9 CAS NO 108050-84-6 is a synthetic nonapeptide fragment of the gastrointestinal hormone cholecystokinin (CCK), specifically the C-terminal octapeptide (CCK-8) with an additional N-terminal glycine residue. This peptide is a critical research tool for studying the physiological and pharmacological roles of CCK receptors in the central nervous system and gastrointestinal tract. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in neuroscience, endocrinology, and drug discovery programs.

Application

• Neuroscience Research: Used as a selective agonist for CCK receptors to study their role in anxiety, satiety, nociception, and memory.
• Gastrointestinal Physiology Studies: Investigates the regulation of pancreatic enzyme secretion, gallbladder contraction, and gut motility.
• Drug Discovery & Development: Serves as a reference standard and pharmacological tool in high-throughput screening (HTS) assays for identifying novel CCK receptor modulators.
• Biochemical Assays: Employed in receptor binding studies, second messenger assays, and functional characterization of CCK receptor subtypes (CCKA and CCKB/gastrin).
• Academic & Clinical Research: Supports fundamental research into the brain-gut axis and the development of potential therapeutics for disorders like panic attacks, obesity, and chronic pain.

Basic Information

Item	Details
Product Name	Cholecystokinin 9
CAS No.	108050-84-6
Molecular Formula	C56H73N13O12S
Molecular Weight	1120.3 g/mol
Synonyms	CCK-9; Cholecystokinin Nonapeptide; Sincalide (related to CCK-8); CCK (26-34), sulfated; H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2; Sulfated Cholecystokinin Fragment (26-34); CCK Octapeptide, N-Gly Extended; Gastrin/CCK-Related Peptide
EINECS	Contact for details

Quality Control

Our Cholecystokinin 9 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide full traceability and Certificates of Analysis (COA) detailing purity, content, and impurity profiles to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere. Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.