Description

Acth, Formylmethionyl- CAS NO 107949-95-1 is a synthetic peptide derivative, specifically a formylated methionine variant of adrenocorticotropic hormone (ACTH). This modification is of significant interest in biochemical and pharmaceutical research for studying receptor interactions and signal transduction pathways. It is primarily utilized by research institutions and pharmaceutical developers focused on endocrinology, peptide chemistry, and the development of novel diagnostic or therapeutic agents.

Application

• Biochemical Research: Used as a key reference standard or tool compound in studies of ACTH receptor binding and activation mechanisms.
• Pharmaceutical Development: Serves as an intermediate or precursor in the synthesis and screening of novel peptide-based therapeutics targeting the hypothalamic-pituitary-adrenal axis.
• Diagnostic Agent Research: Potential use in the development of specialized diagnostic assays and imaging probes related to adrenal function.
• Academic Studies: Employed in university and institutional labs for teaching and advanced research in endocrinology and peptide hormone action.
• Peptide Library Synthesis: Can be incorporated into combinatorial peptide libraries for high-throughput screening and structure-activity relationship (SAR) studies.

Basic Information

Product Name	Acth, Formylmethionyl-
CAS No.	107949-95-1
Molecular Formula	C209H310N56O58S
Molecular Weight	4543.1 g/mol (approx.)
Synonyms	Formylmethionyl-Adrenocorticotropic Hormone; Formyl-Met-ACTH; N-Formylmethionyl-ACTH; fMet-ACTH; ACTH (1-39), N-formylmethionyl-; Adrenocorticotropin, N-formylmethionyl-; N-Formylmethionyl-corticotropin
EINECS	Contact for details

Quality Control

Our Acth, Formylmethionyl- is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Quality is verified through advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.