Description

H-Ala-Ala-Ala-Tyr-Ala-Ala-Oh CAS NO 107865-42-9 is a synthetic hexapeptide featuring a tyrosine residue within an alanine-rich sequence. This specific sequence makes it a valuable tool compound for biochemical research and pharmaceutical development, particularly in studying enzyme-substrate interactions and peptide stability. It is primarily utilized by research institutions and biotechnology companies focused on proteomics, peptide chemistry, and drug discovery.

Application

• Biochemical Research: Used as a model substrate for studying the kinetics and specificity of proteolytic enzymes like chymotrypsin and other serine proteases.
• Pharmaceutical Development: Serves as a reference standard or an intermediate in the synthesis and characterization of more complex therapeutic peptides.
• Proteomics & Enzymology: Employed in assays to investigate protein-peptide interactions, enzyme inhibition, and cleavage site mapping.
• Peptide Library Construction: Acts as a building block or a specific sequence variant in the design and screening of combinatorial peptide libraries for drug discovery.
• Academic Research: Utilized in university laboratories for teaching advanced concepts in peptide synthesis, purification, and analysis.
• Quality Control Standard: Functions as a high-purity standard for calibrating analytical instruments such as HPLC and mass spectrometers in peptide analysis.

Basic Information

Product Name	H-Ala-Ala-Ala-Tyr-Ala-Ala-Oh
CAS No.	107865-42-9
Molecular Formula	C27H40N6O9
Molecular Weight	592.65 g/mol
Synonyms	Ala-Ala-Ala-Tyr-Ala-Ala; A-A-A-Y-A-A; Hexapeptide A3YA3; H-Ala-Ala-Ala-Tyr-Ala-Ala-OH; L-Alanyl-L-alanyl-L-alanyl-L-tyrosyl-L-alanyl-L-alanine; AAAYAA; (Ala)3-Tyr-(Ala)2; N-(L-Alanyl)-L-alanyl-L-alanyl-L-tyrosyl-L-alanyl-L-alanine
EINECS	Contact for details

Quality Control

Our H-Ala-Ala-Ala-Tyr-Ala-Ala-Oh is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure sequence integrity. A Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment to guarantee compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Conforms to theoretical composition
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.