Description

Preproatrial Natriuretic Factor (26-55) is a defined synthetic peptide fragment corresponding to residues 26-55 of the preproatrial natriuretic factor precursor. This peptide is a critical research tool for investigating the structure, function, and processing of natriuretic peptides, which are key regulators of blood pressure, fluid balance, and cardiovascular homeostasis. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies engaged in cardiovascular research, peptide hormone studies, and the development of novel diagnostic assays.

Application

• Biomedical Research: Used as a reference standard and antigen in studies of atrial natriuretic peptide (ANP) biosynthesis, processing, and biological activity.
• Immunoassay Development: Serves as a critical component for the development and calibration of enzyme-linked immunosorbent assays (ELISA) and radioimmunoassays (RIA) targeting ANP and its precursors.
• Antibody Production: Acts as an immunogen for generating specific polyclonal or monoclonal antibodies against the preproANP sequence.
• Structure-Activity Relationship (SAR) Studies: Provides a defined peptide fragment for investigating the relationship between specific regions of the preprohormone and its physiological effects.
• Pharmaceutical Screening: Employed in high-throughput screening assays to identify compounds that modulate the natriuretic peptide system for potential therapeutic applications.
• Diagnostic Reagent Manufacturing: Incorporated into diagnostic kits for the quantitative measurement of ANP-related peptides in clinical and research samples.

Basic Information

Item	Detail
Product Name	Preproatrial Natriuretic Factor (26-55)
CAS No.	107814-70-0
Molecular Formula	C138H218N44O43S2
Molecular Weight	3173.6 g/mol
Synonyms	PreproANP (26-55); Atrial Natriuretic Factor (26-55); ANF (26-55); Cardionatrin (26-55); Atriopeptigen (26-55); rANP(26-55); Synthetic Atrial Natriuretic Peptide Fragment 26-55; Prepro-Atrial Natriuretic Peptide (26-55)
EINECS	Contact for details

Quality Control

Every batch of Preproatrial Natriuretic Factor (26-55) is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency suitable for critical research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting standards. A comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and analytical data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider aliquoting to minimize freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by amino acid analysis)
Molecular Weight	3173.6 ± 2.0 Da (by MS)
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.