Description

Pyroglutamyl-Histidyl-Proline-Tyramine is a synthetic peptide derivative with the CAS registry number 107810-10-6. This compound is of significant interest in advanced biochemical research and development, particularly for its potential role in studying neuropeptide pathways and signal transduction mechanisms. It is primarily utilized by research institutions and pharmaceutical development teams focused on neuroscience, endocrinology, and novel therapeutic agent discovery.

Application

• Neuroscience Research: Used as a reference standard or investigative tool in studying neuropeptide function, receptor binding, and neuronal signaling pathways.
• Pharmaceutical R&D: Serves as a key intermediate or active pharmaceutical ingredient (API) precursor in the development of novel central nervous system (CNS) targeted therapies.
• Biochemical Assays: Employed in in vitro and cell-based assays to elucidate specific biological activities and mechanisms of action related to its peptide sequence.
• Endocrinology Studies: Applied in research exploring the interplay between peptide hormones and metabolic or stress response systems.
• Academic Research: Utilized in university and institutional labs for fundamental studies in peptide chemistry, biochemistry, and molecular biology.
• Peptide Library Synthesis: Acts as a building block or a specialized component in the synthesis of focused peptide libraries for high-throughput screening.

Basic Information

Item	Details
Product Name	Pyroglutamyl-Histidyl-Proline-Tyramine
CAS No.	107810-10-6
Molecular Formula	C29H36N8O7
Molecular Weight	608.65 g/mol
Synonyms	pGlu-His-Pro-Tyr-NH2; Pyroglutamylhistidylprolyltyramine; 5-Oxo-L-prolyl-L-histidyl-L-prolyl-L-tyrosinamide; L-Tyrosinamide, 5-oxo-L-prolyl-L-histidyl-L-prolyl-; TRH-Tyr-NH2; Thyrotropin-Releasing Hormone Tyrosinamide Analog; TRH Tyramine; Contact for details on additional synonyms.
EINECS	Contact for details

Quality Control

Our Pyroglutamyl-Histidyl-Proline-Tyramine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral purity checks, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.