Description

1,6-Anhydromuramyl-Alanyl-Glutamyl-Diaminopimelyl-Alanine is a specialized peptidoglycan fragment, a key structural component of bacterial cell walls. This compound is of significant interest for its role in immunological research and as a critical reference standard in microbiology. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for studying bacterial physiology, immune system activation, and developing novel antibacterial agents. The compound is supplied with a high level of purity to ensure reliable and reproducible experimental results.

Application

• Immunological Research: Used as a defined antigen or ligand to study innate immune responses, particularly the activation of NOD-like receptors (NOD2) and subsequent cytokine production.
• Pharmaceutical R&D: Serves as a critical reference standard and intermediate in the development of novel antibiotics, immunomodulators, and vaccine adjuvants targeting bacterial cell wall synthesis.
• Biochemical Studies: Employed in enzymatic assays to investigate the activity of muramidases, peptidoglycan hydrolases, and other enzymes involved in bacterial cell wall remodeling.
• Microbiology: Used as a structural probe to understand peptidoglycan architecture, cross-linking, and the mechanisms of action of β-lactam antibiotics.
• Quality Control: Acts as a high-purity analytical standard for the identification and quantification of peptidoglycan derivatives in complex biological matrices.

Basic Information

Product Name	1,6-Anhydromuramyl-Alanyl-Glutamyl-Diaminopimelyl-Alanine
CAS No.	107783-60-8
Molecular Formula	C36H58N8O17
Molecular Weight	850.90 g/mol
Synonyms	MurNAc-L-Ala-D-isoGln-meso-DAP-D-Ala; N-Acetylmuramyl-L-alanyl-D-isoglutaminyl-meso-diaminopimelyl-D-alanine; Anhydro-MDP; 1,6-Anhydro-MDP; Muramyl Tetrapeptide; MTP; Anhydro MurNAc-tetrapeptide; Peptidoglycan Monomer (Anhydro form)
EINECS	Contact for details

Quality Control

Our 1,6-Anhydromuramyl-Alanyl-Glutamyl-Diaminopimelyl-Alanine is manufactured under controlled conditions to ensure the highest standards of purity and consistency, suitable for sensitive research applications. Each batch is subjected to a comprehensive suite of analytical tests, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic nature, the container should be allowed to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Bacterial Endotoxins	< 10.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.