Description

Somatotropin Releasing Factor 40, Leu(27)- CAS NO 107761-41-1 is a synthetic peptide analog of growth hormone-releasing hormone (GHRH). This compound is of significant value for research and development in endocrinology and metabolic studies due to its specific biological activity. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on growth hormone regulation, peptide therapeutics, and diagnostic applications.

Application

• Pharmaceutical Research & Development: Used as a reference standard and active ingredient in preclinical studies for growth hormone-related therapies.
• Endocrinology Studies: Critical for investigating the mechanisms of growth hormone secretion and pituitary function.
• Biochemical Assay Development: Serves as a key component in developing and validating in vitro bioassays for GHRH activity.
• Metabolic Disorder Research: Applied in research models exploring treatments for growth disorders and metabolic syndromes.
• Peptide Chemistry & Synthesis: Used as a building block or intermediate in advanced peptide synthesis projects.
• Veterinary Science Applications: Potential use in research for growth promotion and metabolic studies in livestock.

Basic Information

Product Name	Somatotropin Releasing Factor 40, Leu(27)-
CAS No.	107761-41-1
Molecular Formula	C215H358N72O66S
Molecular Weight	~4750.6 g/mol
Synonyms	GHRH (1-40), Leu(27); Leu(27)-hGHRH(1-40)-NH2; Growth Hormone-Releasing Hormone (1-40), human, Leu(27)-; Somatoliberin (1-40), Leu(27)-; GRF (1-40), Leu(27)-; Human GHRH(1-40) amide, [Leu27]; Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Leu-Leu-Gln-Gly-Leu-Val-Arg-Asn-Arg-NH2 (Leu27 variant); [Leu27]hGHRH(1-40)
EINECS	Contact for details

Quality Control

Our Somatotropin Releasing Factor 40, Leu(27)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure compliance with high-purity research-grade standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This hygroscopic and moisture-sensitive material should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and degradation. For long-term stability, store under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum confirms molecular weight
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.