Description

2(1H)-Pyrimidinethione, 4-Mercapto- (9Ci) is a specialized heterocyclic building block featuring a reactive thiol group on the pyrimidine scaffold. This compound is a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel drug candidates, especially in areas like kinase inhibitors and antiviral agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for functionalized polymers and ligands for metal-organic frameworks (MOFs).
• Bioconjugation Chemistry: The reactive thiol group enables site-specific modification of proteins and peptides.
• Chemical Biology Probes: Utilized in the design of probes for studying enzyme mechanisms and biological pathways.
• Catalyst Ligand Synthesis: Acts as a starting material for creating novel ligands used in homogeneous catalysis.

Basic Information

Product Name	2(1H)-Pyrimidinethione, 4-Mercapto- (9Ci)
CAS No.	107686-58-8
Molecular Formula	C4H4N2S
Molecular Weight	112.15 g/mol
Synonyms	4-Mercapto-2(1H)-pyrimidinethione; 4-Mercaptopyrimidine-2(1H)-thione; 4-Mercapto-2-pyrimidinethiol; 2,4-Dimercaptopyrimidine; 4-Thioxo-3,4-dihydropyrimidine-2(1H)-thione; 4-Mercapto-1H-pyrimidine-2-thione; 4-Mercapto-2-thioxo-1,2-dihydropyrimidine
EINECS	Contact for details

Quality Control

Our 2(1H)-Pyrimidinethione, 4-Mercapto- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity, minimize exposure to air and moisture during handling.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.