Description

5-Chloro-4-Iodo-2-(Methylthio)Pyrimidine is a high-value halogenated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its unique structure, featuring chlorine, iodine, and a methylthio group, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by pharmaceutical R&D and agrochemical manufacturers for the development of novel active ingredients, including potential antiviral and anticancer agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of nucleoside analogs, kinase inhibitors, and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for functionalized heterocyclic compounds used in organic electronics and ligand design.
• Chemical Biology: Employed in the synthesis of probes and labeled compounds for biochemical and pharmacological studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific halogenated pyrimidine scaffolds.

Basic Information

Product Name	5-Chloro-4-Iodo-2-(Methylthio)Pyrimidine
CAS No.	107403-27-0
Molecular Formula	C5H4ClIN2S
Molecular Weight	286.52 g/mol
Synonyms	2-(Methylthio)-5-chloro-4-iodopyrimidine; 4-Iodo-5-chloro-2-methylthiopyrimidine; 5-Chloro-4-iodo-2-methylsulfanylpyrimidine; 5-Chloro-4-iodo-2-(methylmercapto)pyrimidine; 2-Methylsulfanyl-5-chloro-4-iodopyrimidine; 5-Chloro-4-iodo-2-(methylsulfanyl)pyrimidine; 4-Iodo-5-chloro-2-(methylthio)pyrimidine
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-4-Iodo-2-(Methylthio)Pyrimidine is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.