Description

L-Isoleucine, 2-Methyl-, Methyl Ester (9Ci) is a high-purity, protected amino acid derivative essential for advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block, enabling the precise construction of complex peptides and bioactive molecules. It is primarily required by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers focused on peptide-based therapeutics and novel drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs, antibiotics, and other active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) for the controlled introduction of the isoleucine residue with a protected carboxyl group.
• Biochemical Research: Employed in proteomics and metabolic pathway studies as a labeled or modified amino acid precursor.
• Fine Chemical Production: Acts as a starting material or intermediate in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Agrochemical Development: Utilized in the research and synthesis of novel, biologically active compounds for crop protection.

Basic Information

Product Name	L-Isoleucine, 2-Methyl-, Methyl Ester (9Ci)
CAS No.	107246-42-4
Molecular Formula	C8H17NO2
Molecular Weight	159.23 g/mol
Synonyms	L-Isoleucine methyl ester; Methyl L-isoleucinate; (2S,3S)-2-Amino-3-methylpentanoic acid methyl ester; (S,S)-Isoleucine methyl ester; H-Ile-OMe; Isoleucine methyl ester hydrochloride (related salt); L-2-Amino-3-methylvaleric acid methyl ester; Methyl (2S,3S)-2-amino-3-methylpentanoate
EINECS	Contact for details

Quality Control

Our L-Isoleucine, 2-Methyl-, Methyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the stringent requirements for pharmaceutical research and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.