Description

2,4-Dimethoxy-5-Iodo-6-Methylpyrimidine is a high-purity halogenated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology & Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Material Science Precursor: Potential intermediate for the synthesis of organic electronic materials and liquid crystals.
• Cross-Coupling Reactions: The iodine substituent makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects.

Basic Information

Product Name	2,4-Dimethoxy-5-Iodo-6-Methylpyrimidine
CAS No.	107166-93-8
Molecular Formula	C7H9IN2O2
Molecular Weight	280.07 g/mol
Synonyms	5-Iodo-2,4-dimethoxy-6-methylpyrimidine; 6-Methyl-2,4-dimethoxy-5-iodopyrimidine; 5-Iodo-6-methyl-2,4-bis(methoxy)pyrimidine; Pyrimidine, 5-iodo-2,4-dimethoxy-6-methyl-; 2,4-Dimethoxy-6-methyl-5-iodopyrimidine
EINECS	Contact for details

Quality Control

Our 2,4-Dimethoxy-5-Iodo-6-Methylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.