Description

Parathyroid Hormone (3-34)Amide is a bioactive synthetic peptide fragment of the parathyroid hormone, a key regulator of calcium and phosphate metabolism. This specific amide derivative is valued for its stability and potent biological activity in research and development settings. It is primarily utilized by pharmaceutical researchers and biotechnology companies engaged in metabolic bone disease studies, osteoporosis research, and the development of novel therapeutic agents.

Application

• Pharmaceutical Research & Development: A critical tool for studying calcium homeostasis, bone remodeling pathways, and the mechanisms of parathyroid hormone action.
• Biochemical Assay Standard: Used as a reference standard or active component in cell-based assays and receptor binding studies to evaluate PTH receptor activity.
• Metabolic Bone Disease Studies: Fundamental for in vitro and in vivo research targeting osteoporosis, hyperparathyroidism, and other disorders of bone mineral metabolism.
• Peptide Chemistry & Analog Development: Serves as a key intermediate or parent structure for synthesizing and testing novel PTH peptide analogs with modified pharmacokinetic profiles.
• Academic & Institutional Research: Supports basic scientific investigations in endocrinology, physiology, and molecular biology within university and government laboratories.

Basic Information

Product Name	Parathyroid Hormone (3-34)Amide
CAS No.	107120-62-7
Molecular Formula	C152H246N44O45S2
Molecular Weight	3481.0 g/mol (approx.)
Synonyms	PTH (3-34) amide; Parathyroid Hormone Fragment 3-34 amide; hPTH (3-34)NH2; [Tyr34]hPTH(3-34)amide; Parathyroid hormone (human 3-34) amide; PTH-related protein analog; PTHrP (1-34) analog (related); Calcium metabolism regulator peptide
EINECS	Contact for details

Quality Control

Our Parathyroid Hormone (3-34)Amide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and residual solvent levels are provided to ensure compliance with research-grade specifications and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.