Description

Mastoparan 5 (9Ci) is a synthetic, amphiphilic peptide analog derived from wasp venom, known for its potent biological activity. This compound is a valuable research tool for studying G-protein coupled receptor (GPCR) signaling pathways and mast cell degranulation mechanisms. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in cell biology, immunology, and drug discovery programs. The product is supplied under strict quality control to ensure batch-to-batch consistency for reliable experimental results.

Application

• GPCR Signaling Research: Acts as a direct activator of heterotrimeric G-proteins (Gi/Go), used to study receptor-independent G-protein function and downstream cellular responses.
• Mast Cell & Immunology Studies: Induces histamine release from mast cells, serving as a key reagent in allergy, inflammation, and anaphylaxis research models.
• Antimicrobial & Anticancer Investigations: Explored for its membrane-disrupting properties against bacteria, fungi, and certain cancer cell lines in preclinical studies.
• Neuroscience & Ion Channel Modulation: Used to examine effects on neuronal exocytosis and the modulation of calcium and potassium ion channels.
• Peptide Chemistry & Drug Design: Serves as a structural template for designing novel bioactive peptides with modified potency, selectivity, or stability profiles.
• Cell Permeabilization Agent: Facilitates the introduction of impermeable molecules into cells for intracellular delivery applications.

Basic Information

Product Name	Mastoparan 5 (9Ci)
CAS No.	107048-34-0
Molecular Formula	C71H121N21O19
Molecular Weight	1564.86 g/mol
Synonyms	Mastoparan 5; Mastoparan V1; Mastoparan-5; Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2; INLKALAALAKKIL-NH2; [Ile1, Asn2, Leu3, Lys4] Mastoparan; Mast cell degranulating peptide 5
EINECS	Contact for details

Quality Control

Our Mastoparan 5 (9Ci) is manufactured under controlled conditions to ensure high purity and biological activity. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and Mass Spectrometry (MS) for identity confirmation. We provide comprehensive Certificates of Analysis (COA) detailing purity, peptide content, and other critical parameters to support your research compliance. Our quality system is designed to meet the stringent requirements of research and pre-clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.