Description

n-Caproyl-L-Homoserine Lactone (C10-AHL) is a specific, high-purity N-acyl homoserine lactone (AHL) signaling molecule used in quorum sensing research. This compound is critical for studying and manipulating bacterial communication pathways, biofilm formation, and virulence in Gram-negative bacteria. It is an essential research tool for microbiologists, molecular biologists, and pharmaceutical developers working in antimicrobial discovery, synthetic biology, and agricultural science.

Application

• Quorum Sensing Research: A key ligand for studying LuxR-type receptor proteins in bacterial cell-to-cell communication systems.
• Biofilm Studies: Used to induce or inhibit biofilm formation in model organisms for developing anti-fouling agents and anti-biofilm strategies.
• Microbial Physiology: Essential for investigating the regulation of virulence factor production, bioluminescence, and other quorum-sensing-controlled phenotypes.
• Drug Discovery: Serves as a reference standard and precursor in the development of quorum sensing inhibitors (QSIs) as novel anti-infective agents.
• Synthetic Biology: Used as a signaling molecule to engineer and control population-density-dependent gene expression in synthetic genetic circuits.
• Agricultural Research: Applied in studies aimed at disrupting pathogenic bacterial communication in crops to develop alternative plant protection methods.

Basic Information

Product Name	n-Caproyl-L-Homoserine Lactone
CAS No.	106983-28-2
Molecular Formula	C14H23NO4
Molecular Weight	269.34 g/mol
Synonyms	N-Hexanoyl-L-homoserine lactone; C6-HSL; N-Caproylhomoserine lactone; N-(3-Oxotetradecanoyl)homoserine lactone; AHL; Autoinducer; Quorum Sensing Molecule; N-(3-Oxododecanoyl)-L-homoserine lactone (related structure); N-Acylhomoserine Lactone
EINECS	Contact for details

Quality Control

Our n-Caproyl-L-Homoserine Lactone is produced under controlled conditions to ensure high chemical purity and biological activity, suitable for sensitive research applications. Each batch is rigorously analyzed using HPLC, NMR, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and meet the stringent requirements of academic and industrial R&D.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, freezer environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	95.0% - 105.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Biological Activity	Tested in standard quorum sensing bioassay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.