Description

3-Methyl-4-(Trifluoromethyl)Phenol is a versatile fluorinated phenolic compound, identified by CAS NO 106889-91-2. This specialty chemical is valued for its unique trifluoromethyl group, which imparts enhanced lipophilicity, metabolic stability, and electronic properties to molecular structures. It serves as a critical advanced pharmaceutical intermediate (API) and a key building block in the synthesis of agrochemicals, liquid crystal materials, and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anti-inflammatory, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a core structural unit in the production of fluorinated liquid crystals and organic light-emitting diode (OLED) materials for high-performance electronic displays.
• Polymer & Resin Modifier: Incorporated into specialty polymers and epoxy resins to improve chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, such as Suzuki and Buchwald-Hartwig couplings, to introduce the phenol and trifluoromethyl motifs into complex molecules.
• Research & Development: Serves as a valuable reagent in academic and industrial R&D for exploring new fluorinated compounds and materials science.

Basic Information

Product Name	3-Methyl-4-(Trifluoromethyl)Phenol
CAS No.	106889-91-2
Molecular Formula	C8H7F3O
Molecular Weight	176.14 g/mol
Synonyms	4-Hydroxy-2-methylbenzotrifluoride; 2-Methyl-4-(trifluoromethyl)phenol; 4-(Trifluoromethyl)-2-methylphenol; 3-Methyl-4-trifluoromethylphenol; 2-Methyl-α,α,α-trifluoro-p-cresol; p-Cresol, 2-methyl-α,α,α-trifluoro-; 2-Methyl-4-hydroxybenzotrifluoride
EINECS	Contact for details

Quality Control

Our 3-Methyl-4-(Trifluoromethyl)Phenol is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.