Description

2-Trifluoromethyl-Benzene-1,3-Diol is a fluorinated aromatic diol compound, serving as a versatile and high-value building block in advanced chemical synthesis. Its unique trifluoromethyl-substituted resorcinol structure imparts desirable properties such as enhanced lipophilicity and metabolic stability to target molecules. This intermediate is critically important for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients with improved efficacy and performance profiles.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in areas like oncology, CNS disorders, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom's bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, resins, and coatings with enhanced chemical resistance.
• Liquid Crystal & OLED Materials: Acts as a core or side-chain component in the synthesis of fluorinated organic electronic materials.
• Organic Synthesis & Catalysis: Employed as a ligand precursor or a directing group in metal-catalyzed cross-coupling reactions.
• Dye & Pigment Intermediate: Used in the manufacture of specialized fluorinated dyes and colorants.

Basic Information

Product Name	2-Trifluoromethyl-Benzene-1,3-Diol
CAS No.	106877-44-5
Molecular Formula	C7H5F3O2
Molecular Weight	178.11 g/mol
Synonyms	2-(Trifluoromethyl)resorcinol; 1,3-Dihydroxy-2-(trifluoromethyl)benzene; 2-Trifluoromethyl-1,3-benzenediol; α,α,α-Trifluororesorcinol; 2-Hydroxy-6-(trifluoromethyl)phenol; 2-CF3-Resorcinol; 2-Trifluoromethylresorcinol; 2-TFM-Resorcinol
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethyl-Benzene-1,3-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP and ISO standards for pharmaceutical and industrial intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.