Description

5-Methoxy-2-(Trifluoromethyl)Phenol is a versatile fluorinated phenolic compound that serves as a key building block in advanced organic synthesis. Its unique structure, featuring both a methoxy group and a trifluoromethyl substituent on the phenol ring, makes it a valuable intermediate for creating molecules with enhanced properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients. Its role is critical in the synthesis of complex molecules where specific electronic and steric characteristics are required.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the production of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs as a standard reagent for studying fluorination effects, reaction mechanisms, and for creating custom chemical libraries.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized dyes and pigments that require specific light-fastness and color properties.

Basic Information

Product Name	5-Methoxy-2-(Trifluoromethyl)Phenol
CAS No.	106877-40-1
Molecular Formula	C8H7F3O2
Molecular Weight	192.14 g/mol
Synonyms	2-Hydroxy-4-methoxybenzotrifluoride; 2-Trifluoromethyl-5-methoxyphenol; 4-Methoxy-2-(trifluoromethyl)phenol; 5-Methoxy-α,α,α-trifluoro-o-cresol; 5-Methoxy-2-(trifluoromethyl)benzenol; 2-(Trifluoromethyl)-5-methoxyphenol; 5-Methoxy-2-trifluoromethylphenol
EINECS	Contact for details

Quality Control

Our production of 5-Methoxy-2-(Trifluoromethyl)Phenol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to verify identity, potency, and impurity profiles. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality system is designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.