Description

2-Trifluoromethyl-6-Chlorophenol is a versatile fluorinated phenolic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both trifluoromethyl and chloro substituents, imparts valuable properties such as enhanced lipophilicity and metabolic stability to target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Used in the production of specialty chemicals for electronic displays and organic light-emitting diodes due to its stable aromatic fluorinated structure.
• Polymer Modification: Serves as a monomer or additive to introduce fluorine into polymer chains, improving chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a protecting group or directing agent in complex multi-step synthetic routes.
• Dye & Pigment Intermediate: Utilized in the manufacture of specialized colorants and photographic chemicals requiring halogenated phenolic components.

Basic Information

Product Name	2-Trifluoromethyl-6-Chlorophenol
CAS No.	106877-36-5
Molecular Formula	C7H4ClF3O
Molecular Weight	196.55 g/mol
Synonyms	6-Chloro-2-(trifluoromethyl)phenol; 2-Chloro-6-(trifluoromethyl)phenol; 2-Trifluoromethyl-6-chlorophenol; 1-Chloro-3-hydroxy-2-(trifluoromethyl)benzene; Phenol, 2-chloro-6-(trifluoromethyl)-; o-Chloro-α,α,α-trifluoro-m-cresol; 2-CF3-6-Cl-Phenol
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethyl-6-Chlorophenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. The compound is light-sensitive; store away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	42 - 46 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.