Description

2-Trifluoromethyl-5-Chlorophenol is a halogenated phenol derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique trifluoromethyl and chloro substituents impart valuable properties, making it essential for creating compounds with enhanced stability and bioactivity. This intermediate is primarily sought after by the pharmaceutical and agrochemical industries for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring trifluoromethylated aromatic systems.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group improves lipophilicity and metabolic stability.
• Liquid Crystal Materials: Acts as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Polymer Chemistry: Serves as a monomer or modifier for creating specialty polymers with specific chemical resistance or surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic aromatic substitution, and other transformations to introduce functionalized phenolic structures.

Basic Information

Product Name	2-Trifluoromethyl-5-Chlorophenol
CAS No.	106877-35-4
Molecular Formula	C7H4ClF3O
Molecular Weight	196.55 g/mol
Synonyms	5-Chloro-2-(trifluoromethyl)phenol; 5-Chloro-α,α,α-trifluoro-o-cresol; 2-Chloro-5-hydroxybenzotrifluoride; 3-Chloro-6-hydroxybenzotrifluoride; 2-Trifluoromethyl-5-chlorophenol; Phenol, 5-chloro-2-(trifluoromethyl)-; o-Trifluoromethyl-p-chlorophenol
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethyl-5-Chlorophenol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.