Description

3-Methyl-4-Trifluoromethylaniline is a versatile fluorinated aromatic amine building block, prized for its unique combination of a reactive aniline group and a stable trifluoromethyl substituent. This compound is essential for introducing lipophilicity and metabolic stability into target molecules, making it a critical intermediate in advanced synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas like kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Material Science: Serves as a monomer or precursor for specialty polymers, liquid crystals, and organic electronic materials requiring specific fluorine content.
• Dye and Pigment Manufacturing: Acts as an intermediate for creating high-performance, light-fast fluorinated dyes and pigments.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and as a precursor for heterocyclic compounds in academic and industrial R&D.

Basic Information

Product Name	3-Methyl-4-Trifluoromethylaniline
CAS No.	106877-31-0
Molecular Formula	C8H8F3N
Molecular Weight	175.15 g/mol
Synonyms	4-(Trifluoromethyl)-3-methylaniline; 3-Methyl-4-(trifluoromethyl)aniline; 3-Methyl-α,α,α-trifluoro-p-toluidine; 4-Amino-2-methylbenzotrifluoride; 2-Methyl-4-aminobenzotrifluoride; Benzenamine, 3-methyl-4-(trifluoromethyl)-; 3-Methyl-4-trifluoromethylphenylamine
EINECS	Contact for details

Quality Control

Our production of 3-Methyl-4-Trifluoromethylaniline adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our facility operates under cGMP principles where applicable, ensuring traceability and reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.