Description

4-Amino-2,2-difluoro-1,3-benzodioxole is a high-purity, specialty aromatic heterocyclic compound featuring a benzodioxole core with amino and difluoro substituents. This unique molecular structure makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block for synthesizing complex organic molecules. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the fluorine atoms enhance biological activity and stability.
• Material Science Research: Serves as a building block for creating specialized polymers, ligands, or fluorinated organic frameworks with unique electronic or surface properties.
• Organic Synthesis & Catalysis: Employed as a versatile reagent in complex organic transformations, including cross-coupling reactions and the construction of heterocyclic systems.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory compliance in chemical manufacturing.

Basic Information

Product Name	4-Amino-2,2-difluoro-1,3-benzodioxole
CAS No.	106876-54-4
Molecular Formula	C7H5F2NO2
Molecular Weight	173.12 g/mol
Synonyms	2,2-Difluoro-4-amino-1,3-benzodioxole; 4-Amino-2,2-difluorobenzodioxole; 1,3-Benzodioxole, 4-amino-2,2-difluoro-; 2,2-Difluoro-1,3-benzodioxol-4-amine; 4-Amino-2,2-difluoro-1,3-benzodioxole; 106876-54-4; 4-Amino-2,2-difluorobenzo[d][1,3]dioxole
EINECS	Contact for details

Quality Control

Our 4-Amino-2,2-difluoro-1,3-benzodioxole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.