Description

Insulin-Like Growth Factor I, n-Methionyl- is a recombinant protein analog of human IGF-1, engineered with an additional N-terminal methionine residue. This modification enhances its stability and makes it a critical reagent in advanced biopharmaceutical research and development. It is essential for researchers and manufacturers in the life sciences sector, particularly for applications in cell culture, metabolic studies, and the development of therapeutic agents targeting growth and metabolic pathways.

Application

• Cell Culture & Tissue Engineering: Used as a key growth supplement in serum-free media formulations to promote cell proliferation and differentiation.
• Biopharmaceutical R&D: Serves as a reference standard and active ingredient in research for developing treatments related to growth disorders and metabolic diseases.
• Metabolic Pathway Studies: Employed in biochemical assays to investigate the insulin-like growth factor signaling cascade and its role in cellular metabolism.
• Protein Interaction Research: Utilized in binding studies, ELISA development, and other analytical techniques to study receptor-ligand interactions.
• Stem Cell Research: Supports the maintenance and directed differentiation of various stem cell lines in controlled culture environments.

Basic Information

Product Name	Insulin-Like Growth Factor I, n-Methionyl-
CAS No.	106768-76-7
Molecular Formula	C332H527N97O101S8
Molecular Weight	~7649.0 g/mol
Synonyms	Methionyl-IGF-I; Recombinant IGF-I; IGF-I (1-70), N-methionyl-; Long R3 IGF-I; Des(1-3)IGF-I; Insulin-like growth factor I (human); Somatomedin C; IGF-1; meIGF-I
EINECS	Contact for details

Quality Control

Our Insulin-Like Growth Factor I, n-Methionyl- is produced under stringent conditions to ensure the highest standards of purity and biological activity. Each batch is subjected to a comprehensive suite of analytical tests, including HPLC for purity, mass spectrometry for identity confirmation, and bioassays for potency. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with research-grade and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the lyophilized powder desiccated. Avoid repeated freeze-thaw cycles of reconstituted solutions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Mass Spec)	Conforms
Purity (HPLC)	≥ 95.0%
Biological Activity (Cell-based assay)	Fully active
Endotoxin Level (LAL)	< 1.0 EU/µg
Water Content (KF)	< 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.