Description

Glp-1 (7-37) CAS NO 106612-94-6 is a bioactive peptide fragment of the endogenous glucagon-like peptide-1, playing a critical role in glucose metabolism and insulin secretion. This high-purity synthetic peptide is essential for advanced pharmaceutical research and development, particularly in the fields of metabolic disease and diabetes therapeutics. It serves as a key reference standard and active pharmaceutical ingredient (API) intermediate for researchers and manufacturers in the biopharmaceutical and life sciences industries.

Application

• Pharmaceutical R&D: Used as a reference standard and key intermediate in the development of novel GLP-1 receptor agonists and related diabetes treatments.
• Biochemical Research: Critical for in vitro and in vivo studies investigating the mechanisms of insulin secretion, β-cell function, and glucose homeostasis.
• Peptide Synthesis: Serves as a building block or precursor for the synthesis of longer, modified GLP-1 analogs with enhanced stability or activity.
• Quality Control: Employed as an analytical standard in HPLC and MS methods to ensure the purity and identity of GLP-1-based drug substances.
• Academic Research: Utilized in university and institutional labs for fundamental research into incretin biology and peptide hormone signaling pathways.

Basic Information

Product Name	Glp-1 (7-37)
CAS No.	106612-94-6
Molecular Formula	C149H226N40O45
Molecular Weight	3350.7 g/mol
Synonyms	Glucagon-like peptide 1 (7-37); GLP-1 (7-37); Incretin hormone fragment; H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH; GLP1 (7-37); Glucagon-Like Peptide-1 (7-37) (human)
EINECS	Contact for details

Quality Control

Our Glp-1 (7-37) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and tests for related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to warm to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Peptides (HPLC)	≤ 5.0% total
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 80.0%
Acetate Content (HPLC/IC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.