Description

Cyclo(Glutamyl-Leucyl-Prolyl-Glycyl-Lysyl-Leucyl-Prolyl-Glycyl)Cyclo(1-γ-5-Epsilon)Glycine is a synthetic cyclic peptide with a complex, constrained structure designed for enhanced stability and biological activity. This compound matters for researchers and developers seeking advanced peptide-based tools for studying protein-protein interactions and cellular signaling pathways. It is primarily needed by the pharmaceutical, biotechnology, and advanced life science research sectors for applications in drug discovery, biochemical assay development, and as a potential scaffold for novel therapeutics.

Application

• Pharmaceutical Research: Used as a reference standard or active pharmaceutical ingredient (API) intermediate in the development of novel peptide-based drugs targeting specific receptors.
• Biochemical Assays: Serves as a high-affinity ligand or inhibitor in enzyme-linked immunosorbent assays (ELISAs), receptor binding studies, and other in vitro diagnostic tests.
• Cell Biology Studies: Employed to modulate specific cellular pathways, investigate signal transduction mechanisms, or study apoptosis and cell proliferation.
• Cosmeceutical Development: Explored for potential anti-aging or skin-repair properties in high-end cosmetic and dermatological formulations due to its peptide structure.
• Academic Research: A valuable tool in universities and research institutes for fundamental studies in peptide chemistry, structural biology, and medicinal chemistry.
• Bioconjugation: Acts as a specialized building block or linker for creating peptide-drug conjugates or other complex biomolecules.

Basic Information

Item	Details
Product Name	Cyclo(Glutamyl-Leucyl-Prolyl-Glycyl-Lysyl-Leucyl-Prolyl-Glycyl)Cyclo(1-γ-5-Epsilon)Glycine
CAS No.	106372-74-1
Molecular Formula	C44H68N12O12
Molecular Weight	933.1 g/mol
Synonyms	Cyclo(Glu-Leu-Pro-Gly-Lys-Leu-Pro-Gly)Cyclo(1-γ-5-ε)Gly; Cyclic Peptide 106372-74-1; c[Glu-Leu-Pro-Gly-Lys-Leu-Pro-Gly]c(1-γ-5-ε)Gly; (1-γ-5-ε)-Glycine, cyclo[L-glutamyl-L-leucyl-L-prolylglycyl-L-lysyl-L-leucyl-L-prolylglycyl]-, cyclic (1→5)-peptide; GLPGKLPG Cyclic Peptide Derivative; Cyclo(ELPGKLPG)Glycine Lactam Bridge; Peptide Inhibitor 106372-74-1
EINECS	Contact for details

Quality Control

Our Cyclo(Glutamyl-Leucyl-Prolyl-Glycyl-Lysyl-Leucyl-Prolyl-Glycyl)Cyclo(1-γ-5-Epsilon)Glycine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure compliance with high-purity standards suitable for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to prevent degradation. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in DMSO, slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.