Description

(D-Ala1)-Peptide T Amide is a synthetic peptide analog of the HIV envelope glycoprotein gp120, specifically designed for research applications. This compound is a valuable tool in immunological and neurological studies due to its role as a CD4 receptor ligand. It is primarily utilized by research scientists and pharmaceutical developers in the fields of virology, immunology, and neuropharmacology for investigating HIV entry mechanisms and related therapeutic pathways.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of HIV-1 envelope protein interactions with the CD4 receptor.
• Immunological Assays: Employed in the development and validation of assays to study T-cell function and immune response modulation.
• Neuroscience Research: Investigated for its potential neuromodulatory and neuroprotective effects, relevant to HIV-associated neurocognitive disorders (HAND).
• Drug Discovery: Serves as a key intermediate or reference compound in the development of novel antiviral and immunomodulatory therapeutics.
• Academic & Pharmaceutical R&D: Essential for basic research in virology and applied research in vaccine and therapeutic development pipelines.

Basic Information

Product Name	(D-Ala1)-Peptide T Amide
CAS No.	106362-34-9
Molecular Formula	C₄₆H₆₈N₁₂O₁₂
Molecular Weight	981.1 g/mol
Synonyms	Peptide T (D-Ala1) amide; D-Alanine-Peptide T amide; [D-Ala1]-Peptide T; H-D-Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr-NH2; AIDS-related Peptide T analog; CD4-binding peptide analog; HIV envelope gp120 fragment (D-Ala1)
EINECS	Contact for details

Quality Control

Our (D-Ala1)-Peptide T Amide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade specifications. Custom synthesis and purity grades are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep containers sealed under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC-MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content (AAA)	≥ 80%
Solubility	Soluble in water, DMSO, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.