Description

(D-Ala1)-Peptide T CAS NO 106362-33-8 is a synthetic peptide analog of the HIV envelope protein gp120, specifically designed with a D-alanine substitution at the N-terminal position. This modification enhances its metabolic stability and resistance to enzymatic degradation, making it a critical research tool for studying viral entry mechanisms and immune modulation. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in immunology, virology, and therapeutic peptide development.

Application

• Biomedical Research: Investigation of HIV-1 gp120 interactions with CD4 receptors and chemokine co-receptors.
• Immunology Studies: Exploration of neuroimmunomodulatory pathways and cytokine release profiles.
• Drug Discovery: Serving as a reference standard or lead compound in the development of novel antiviral and immunomodulatory agents.
• Diagnostic Development: Potential use in assay development for detecting specific immune responses or viral components.
• Academic & Preclinical Studies: Fundamental research on peptide structure-activity relationships (SAR) and metabolic stability.

Basic Information

Product Name	(D-Ala1)-Peptide T
CAS No.	106362-33-8
Molecular Formula	C46H68N12O12
Molecular Weight	981.1 g/mol
Synonyms	Peptide T (D-Ala1); D-Alanine-Peptide T; [D-Ala1]-Peptide T; AIDS-related Peptide T analog; H-D-Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr-OH; HIV envelope gp120 fragment (D-Ala1); Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr (D-Ala1)
EINECS	Contact for details

Quality Control

Our (D-Ala1)-Peptide T is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. For custom synthesis or specific purity requirements (e.g., >95%, >98%), please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For short-term use, store at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.