Description

2-Methylene-Cyclopropane-1,1-Dicarboxylic Acid Diethyl Ester is a specialized diester derivative of a methylenecyclopropane dicarboxylic acid, serving as a versatile and reactive synthetic building block. Its unique strained-ring structure with an exocyclic methylene group makes it a valuable precursor for constructing complex molecular frameworks through cycloaddition and functionalization reactions. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly those containing strained carbocyclic or spirocyclic systems.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with unique modes of action.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials with tailored properties.
• Organic Synthesis Building Block: Employed in Diels-Alder reactions, [2+2] cycloadditions, and other ring-forming transformations to create complex organic molecules.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme mechanisms.
• Ligand and Catalyst Development: Acts as a precursor for creating novel chelating ligands and organometallic catalysts.

Basic Information

Product Name	2-Methylene-Cyclopropane-1,1-Dicarboxylic Acid Diethyl Ester
CAS No.	106352-19-6
Molecular Formula	C11H16O4
Molecular Weight	212.24 g/mol
Synonyms	Diethyl 2-Methylenecyclopropane-1,1-dicarboxylate; 1,1-Cyclopropanedicarboxylic Acid, 2-Methylene-, Diethyl Ester; Diethyl 2-Methylidenecyclopropane-1,1-dicarboxylate; 2-Methylene-1,1-cyclopropanedicarboxylic Acid Diethyl Ester; Methylenecyclopropane Diethyl Diester; Ethyl 2-Methylenecyclopropane-1,1-dicarboxylate; (2-Methylenecyclopropane-1,1-diyl)bis(oxy)bis(ethane-2,1-diyl) dicarboxylate (IUPAC); MCPD Diethyl Ester
EINECS	Contact for details

Quality Control

Our 2-Methylene-Cyclopropane-1,1-Dicarboxylic Acid Diethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR), to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable batch-to-batch consistency for your synthetic processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.